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Somatropin HGH Online Information
Somatropin® [somatropin (rDNA origin) for injection] is a human growth hormone produced by recombinant DNA technology. Somatropin® has 191 amino acid residues and a molecular weight of 22,125 daltons. Its amino acid sequence and structure are identical to the dominant form of human pituitary growth hormone.
How Somatropin is made for Bio-Identical HGH Therapy
Somatropin® is produced by a mammalian cell line mouse C127 that has been modified by the addition of the human growth hormone gene. Somatropin®, with the correct three-dimensional configuration, is secreted directly through the cell membrane into the cell-culture medium for collection and purification. Somatropin® Human Growth Hormone is a highly purified preparation and the biological potency is determined by measuring the increase in body weight induced in hypophysectomized testing.
Somatropin® is a sterile, non-pyrogenic, white, lyophilized powder intended for subcutaneous or intramuscular injection after reconstitution with Bacteriostatic Water for Injection, USP (0.9% Benzyl Alcohol). The reconstituted solution has a pH of 6.5 to 8.5.
In what dosages can I buy Somatropin Growth Hormone
Somatropin® is available in 5 mg and 8.8 mg vials. The quantitative composition of HGH per 5mg per vial is 5 mg somatropin, 34.2 mg sucrose and 1.16 mg O-phosphoric acid. The pH is adjusted with sodium hydroxide or O-phosphoric acid.
The quantitative composition of HGH per 8.8mg vial is 8.8 mg somatropin, 60.2 mg sucrose and 2.05 mg O-phosphoric acid. The pH is adjusted with sodium hydroxide or O-phosphoric acid.
The diluent is Bacteriostatic Water for Injection, USP containing 0.9% Benzyl Alcohol added as an antimicrobial preservative.
Purchasing Somatropin HGH Pens Online
Somatropin® is available in the Somatropin Pen®, One. Click, HGH Injection Devices2 and Easypod somatropin delivery systems and reconstitution device. The quantitative composition of HGH per cartridge vial contained in the Somatropin pen devices you can buy is as follows:
8.8 mg vial contained in the click.easy® device: Each vial contains 8.8 mg somatropin, 60.2 mg sucrose, and 2.05 mg O-phosphoric acid. The pH is adjusted with sodium hydroxide or O-phosphoric acid.
4 mg vial contained in the click.easy® device: Each vial contains 4 mg somatropin, 27.3 mg sucrose and 0.9 mg O-phosphoric acid. The pH is adjusted with sodium hydroxide or O-phosphoric acid.
The diluent in the click.easy® device contains 0.3% (w/v) metacresol in Sterile Water for Injection added as an antimicrobial preservative. The reconstituted solution has a pH of 6.5 to 8.5.
Somatropin Growth Hormone Facts
Somatropin® HGH is one of the leading bioidentical medications used in HRT for the treatment of human growth hormone deficiency in adults (AGHD) and in children. Manufactured by pharmaceutical company Somatropin EMD Somatropin, Somatropin Somatropin has been providing health and anti-aging benefits for individuals dealing with the effects of AGHD – adult growth hormone deficiency. Somatropin growth hormone has the following medical indications in adults: To correct a deficiency resulting from a pituitary tumor, cancer, radiation therapy, trauma, hypothalamic disease, or other illness. To replenish the missing supply associated with age-related decline. Before prescribing Somatropin Human Growth Hormone, a hormone replacement specialist will examine your blood tests to ensure that a low HGH condition exists. The information gathered from hormone lab test analysis also provides the medical basis for the determination of your somatropin treatment dosage and usage. Each patient also undergoes a medical physical examination by a licensed doctor, and a complete medical history assists your endocrinologist with designing an individualized HGH Replacement Therapy program. There are a number of delivery methods for self-administration when looking to buy Somatropin human growth hormone for therapy. In addition to the traditional needle and syringe method for sale online, you can take your Somatropin shots using a convenient pen device.
Somatropin HGH Pen Devices for Sale
Somatropin Easy, Click® – this is an HGH pen device that automatically inserts a needle and administers a present dosage of HGH into the body. It is used with Somatropin 8.8 mg click.easy cartridges that are mixed in the Somatropin Pen disposable reconstitution device prior to usage. The preset dosing feature eliminates the daily step of dialing the correct dosage.
Somatropin HGH Injection Devices 2® – a needle-free HGH delivery system available for adults who do not want to use a needle. The medication is dispersed through the skin by a spring mechanism. It has a digital display and is used with Somatropin 5 mg and 8.8 mg vials that must first be reconstituted with bacteriostatic water solution.
Somatropin One.Click® – an automatic injector pen unit that contains replaceable cartridges and a dial dosing system. The pen unit is held against the skin while the yellow button is pushed. Hold the unit in place for at least 5 seconds to ensure all the Somatropin medicine is injected.
Somatropin Easypod® – another needle-free HGH delivery device available for adults who do not want to use a needle. The medication is dispersed through the skin by a spring mechanism. It has a digital display and is used with Somatropin 5 mg and 8.8 mg vials that must first be reconstituted with bacteriostatic solution.
The doctors and medical staff at Advance Therapy HRT® are available to answer any questions or address any concerns during our regular business hours. Please contact us for a free consultation to learn more about Somatropin or any of the other excellent brands of HGH that we offer.
Somatropin Summary and Prescription Facts
Somatropin is a Human Growth Hormone produced by recombinant DNA technology: it has 191 amino acid residues, a molecular weight of 22KD and an identical amino acid sequence and structure, to the dominant form of human pituitary growth hormone. Somatropin is produced by a mammalian cell line (mouse C127) that has been modified by the addition of the human growth hormone gene.
Somatropin is a sterile, non-pyrogenic, white, lyophilized powder intended for subcutaneous injection after reconstitution with Bacteriostatic Water for Injection, USP (0.9% Benzyl Alcohol). The reconstituted solution has a pH of 6.5 to 8.5. It comes in 1 vial x 8mg 24IU (automatically reconstituted), and contains 8.8 mg somatropin, 60.2 mg sucrose and 2.05 mg O-phosphoric acid. The pH is adjusted with sodium hydroxide or O-phosphoric acid.
Somatropin Somatropin Bio-Chemical Action
Somatropin Somatropin binds to dimeric growth hormone receptors located within the cell membranes of target tissue cells resulting in intracellular signal transduction and pharmacodynamic effects: skeletal, cell and organ growth, protein synthesis (increased uptake of amino acids and nitrogen retention), carbohydrate metabolism, lipolysis, mineral metabolism (retention of total body potassium, phosphorus, and sodium), connective tissue and bone metabolism (increased synthesis of chondroitin sulphate, collagen and increased excretion of hydroxyproline).
Somatropin is indicated for the treatment of pediatric patients with growth failure due to inadequate secretion of endogenous growth hormone.
In adults, Somatropin is medically indicated for HGH Hormone replacement in either:
The Adult Onset GHD: growth hormone deficiency alone or associated with multiple hormone deficiencies (hypopituitarism), as a result of pituitary disease, hypothalamic disease, surgery, radiation therapy, or trauma
The Childhood Onset GHD resulting from congenital, genetic, acquired, or idiopathic causes.
Patients with closed epiphyses should be re-evaluated before continuation of somatropin therapy.
Somatropin Safety information
Before prescribing Somatropin, doctor should look out for the following:
Male patients with one or more of the known risk factors are at greater risk;
Neoplasms: patients with pre-existing tumours should be monitored for progression or recurrence, as well as for potential malignant transformation of skin lesions, i.e. increased growth of pre-existing nevi. Childhood cancer survivors if treated with somatropin, hold the increased risk of a second neoplasm, especially meningiomas in those treated with radiation to the head for their first neoplasm;
Treatment with somatropin may reduce sensitivity to insulin, especially at high doses in susceptible patients (obese, with Turner syndrome, or with family history of Diabetes mellitus) thus glucose levels should be monitored in all patients; especially in diabetic patients – dosage of concurrent anti-hyperglycaemic drugs (like insulin, oral agents) may require adjustment.
Intracranial Hypertension with papilledema, visual changes, headache, nausea, and/or vomiting have been reported in a few cases; such symptoms normally present at 8 weeks after the initiation of somatropin therapy, and can be reversed by reducing the dose or terminating the treatment; those with Turner syndrome and Prader-Willi Syndrome may be at higher risk to develop IH;
Fluid retention – frequent in adults, like oedema, arthralgia or carpal tunnel syndrome. Dose reduction is required in such cases;
Other hormone replacement therapies should be monitored closely due to an increased risk for hypopituitarism;
Hypothyroidism can become evident or get worse in patients with GHD ;
Patients with Turner syndrome are at risk of autoimmune thyroid disease and primary hypothyroidism
Children with the onset of a limp or hip/knee pain should be evaluated for slipped capital femoral epiphysis
Pre-existing scoliosis may worsen in rapidly growing pediatric patients
Those with Turner syndrome are at higher risk of ear and hearing disorders, e.g. otitis media and also cardiovascular disorders such as stroke, aortic aneurysm/dissection or hypertension;
Injection site rotation is necessary to avoid tissue atrophy;
Local or systemic allergic reactions are possible;
Serum levels of inorganic phosphorus, alkaline phosphatase, parathyroid hormone (PTH) and IGF-I may increase;
Pancreatitis should be considered in patients with persistent severe abdominal pain.
Physicians before prescribing Somatropin or any alternative drugs containing BA should consider the total daily metabolic load of benzyl alcohol.
Once Somatropin HGH therapy is started, risks and side effects of continuing Somatropin HGH should be evaluated if the patient has any of the following: scoliosis, diabetes, cancer, hormone deficiencies, trauma, complains about hip or knee pains, limping, or difficulty breathing. Tests for blood glucose and funduscopic examination (an eye test for intracranial hypertension) must be performed before starting the treatment and periodically afterwards.
HGH Side effects that may arise after the treatment with Somatropin include edema (water retenetion), muscle aches, headaches, numbness, swelling, loss of fatty tissue under the skin, lipoatrophy, irritation or rash at the injection sites. Rotating injection sites for your Somatropin shot can help reduce irritation and adjusting the dosage can help alleviate most symptoms of HGH overuse.
HGH Side effects
Medical HGH side effects of overdose include: extreme edema or water retention, bloating, pain, numbness, tingling sensation in the feet, redness or swelling at the injection site, hypothyroidism, hypoglycaemia, muscle and joint pain, seizures or convulsions, and worsening of psoriasis symptoms that may have existed before hormone treatment began.
In adults carpal tunnel syndrome is a very common symtom of HGH overdose, arthralgia, myalgia, paraesthesia and hypaesthesia have also been reported.
Contraindications of using Somatropin
Somatropin is contraindicated in following patients:
Formulation with benzyl alcohol must not be used in premature babies or neonates;
With acute critical illnesses: due to the complications following multiple accidental trauma, acute respiratory failure, open heart surgery or abdominal surgery;
With cancer/ active malignancy; in case of recurrent activity, somatropin should be discontinued; must not be used in presence with evidence of progression or recurrence of an intracranial tumour or in presence of pituitary tumour;
With active proliferative or severe non-proliferative diabetic retinopathy;
With known hypersensitivity to somatropin or any of its excipients, localised reactions in such cases are the most common;
With closed epiphyseal plates,
Severely obese, with history of upper airway obstruction, sleep apnoea, or with respiratory impairment with Prader-Willi Syndrome.
Somatropin Dosage and Administration
Somatropin should be administered subcutaneously usually in the belly fat, buttocks, hips or thigh. Dosage and administration schedule should be individualized for each patient:
In pediatric GHD, the recommended weekly dosage is 0.18 mg/kg of body weight, and should be divided into equal doses given either on 3 alternate days, 6 times per week or daily
In adult GHD two approaches may be followed: a weight-based regimen (starting with no more than 0.005 mg/kg daily, which may be increased by 0.01 mg/kg/day after 4 weeks) or a non-weight-based regimen (starting with 0.2 mg/day (range, 0.15-0.30 mg/day) which can be increased gradually every 1 to 2 months by 0.1 to 0.2 mg/day, according to clinical response and serum IGF-1 concentrations)
Older men and women HGH treatment patients prone to adverse side effects should start with a lower dose and smaller dose increments, whereas estrogen-deficient women or those using oral estrogen may need higher doses. While Somatropin has weight loss medical benefits, has anabolic and fat burning properties, it is not a weight loss prescription drug and obese patients should not be treated with a weight-loss regimen using excessive growth hormone doses as it may cause adverse side effects.
HGH Overdose or Abuse
Short-term over dosage could lead to hypoglycaemiaor even to hyperclycaemia, and fluid retention. Long-term over dosage can cause signs and symptoms of gigantism and acromegaly.
Somatropin HGH Storage
Keep refrigerated (36°-46° F/2°-8° C). Do not freeze or use after the expiration date. do not use Saizien if the solution is cloudy or particles appear in the injectable solution.
SOMATROPIN HUMAN GROWTH HORMONE is used by endocrine physicians to treat hormone deficiency and imbalance in adult men and women, as well as children. As men and women age, they naturally produce less natural human growth hormone which causes age related symptoms and health conditions. We are the leading Growth Hormone Treatment experts in the United States and with over 20,000 patients served nationwide, we can provide the best service and pricing for Somatropin HGH. Contact us at 866-342-5444 for more HRT info and low somatropin pricing.
Human Growth Hormone deficiency symptoms and related health problems include excessive weight gain, loss of sex drive, muscle loss and weakness, fatigue, insomnia, hot flashes, night sweats, mood swings, dry skin and hair, bone loss, muscle aches, joint pain, sadness, social withdrawal and depression.
With HRT or hormone replacement therapy using natural or bio-identical hormones like Somatropin HGH injections (Human Growth Hormone), Testosterone, HCG, DHEA, Progesterone, Thyroid and others, age management physicians can restore lost or low hormone levels and alleviate symptoms. A simple hormone blood test is usually all that is required in order to determine if you have a hormonal imbalance, an HGH deficiency or low testosterone.
If you think you may have a hormonal imbalance, contact us at Advance Therapy to schedule a Hormone Level Lab Test – Get Hormone Testing Info
Most signs and symptoms of aging coincide with hormone loss or imbalance, especially HGH, Testosterone, Estrogen, Progesterone, DHEA and Melatonin. A simple blood test can tell you if you are hormone deficient. Read more about Somatropin HGH below and fill out the Quick Hormone Info Form for a Free Health Consultation to find out more about Human Growth Hormone and other hormone therapies like Testosterone and HCG.
SOMATROPIN Sales – Somatropin Pen®, One.Click®, HGH Injection Devices 2®
Purchase the Somatropin Somatropin Pen Pen – compact HGH pen device to mix Somatropin for quick reconstitution.
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HOW TO GET A SOMATROPIN PRESCRIPTION FROM YOUR DOCTOR
SOMATROPIN and Bio-Identical HGH is somatropin rDNA origin for injection and a prescription growth hormone therapy for adult men and women. To get prescribed Somatropin HGH injections you will have your hormone blood levels tested, a physical examination and medical assessment. A licensed physician with HRT experience supervises the testing, diagnoses and prescribing of your Somatropin treatment program. Obtaining a prescription for HGH from your doctor is the only legal way to get real injectable growth hormone.
Somatropin HGH for Sale – How to Buy Somatropin HGH Online