Name of the medicinal product Norditropin NordiLet 5mg/1.5ml (15IU) Pre-filled pen,
solution for injection
Composition
Norditropin NordiLet is a solution for injection into the skin in a multi-dose disposable pre-filled pen. Norditropin NordiLet contains biosynthetic human growth hormone (somatropin), which is the active substance. Other ingredients are: Mannitol, histidine, poloxamer 188, phenol and water for injections.
Pharmacotherapeutic group
Somatropin is an endocrine hormone with metabolic and growth promoting effects.
Indications
Children:
Growth failure due to growth hormone insufficiency, growth failure in girls due to gonadal dysgenesis (Turner syndrome), growth retardation in prepubertal
children due to chronic renal disease and short children born small for gestational age ( SGA).
Adults:
Pronounced growth hormone deficiency in known hypothalamicpituitary disease (one other deficient axis, other than prolactin), demonstrated by one provocative test after institution of adequate replacement therapy for any other deficient axis. Childhood onset growth hormone insufficiency, reconfirmed by two provocative tests. In adults, the insulin tolerance test is the provocative test of choice. When the insulin tolerance test is contraindicated, alternative provocative tests must be used. The combined arginine-growth hormone releasing hormone is recommended. An arginineor glucagon test may also be considered; however these tests have less established diagnostic value than the insulin tolerance test.
Dosage and administration
Norditropin NordiLet is a pre-filled pen, which is designed to be used with NovoFine needles. The dose is delivered in clicks. Norditropin NordiLet delivers 1–29 clicks in increments of 1 click for each injection. The dose per click is 0.1333mg (10mg/1.5ml). In the package leaflet for each strength a range of doses in mg per number of clicks is given in a conversion table. The dosage is individual. Generally, daily subcutaneous injection in the evening is recommended. The injection site should be varied to prevent lipoatrophy. Prescription only. For the injection procedure, please
see the instruction manual for Norditropin NordiLet 10mg/1.5ml.Patients should be reminded to wash their hands thoroughly with soap and water and/or disinfectant
prior to any contact with Norditropin NordiLet. Norditropin NordiLet should not be shaken vigorously at any time. General recommendations for dosages are shown
below.
Children:
Growth hormone insufficiency:
25 to 35 microgram/kg/day or 0.7 to 1.0mg/m²/day In children with Turner syndrome: 45 to 67 microgram/kg/day or 1.3 to 2.0mg/m²/day In children with Chronic renal disease: 50 microgram/kg/day or 1.4mg/m²/day In children born small for gestational age (SGA): 33 to 67 microgram/kg/day or 1.0 to 2.0mg/m²/day
Adults:
Replacement therapy: It is recommended to start treatment with a low dose 0.1–0.3mg/day and to increase the dosage gradually at monthly intervals in order to meet the need of the individual patient. Serum IGF–I can be used as guidance for the dose titration. Dose requirementsdecline with age. Maintenance dosages vary from person to person, but seldom exceed 1.0mg/day (equal to 3 IU/day).
Contraindications
Any evidence of active malignant tumours. Intracranial neoplasm must be inactive and antitumour therapy should be completed prior to institution of therapy. Pregnancy and lactation. Patients with acute critical illness suffering complications following open heart surgery, abdominal surgery, multiple accidental trauma, acute respiratory failure or similar conditions should not be treated with Norditropin NordiLet. Hypersensitivity to any of the ingredients in the preparation. In children with chronicrenal disease treatment with Norditropin NordiLet should be discontinued
at renal transplantation.
All pens come prefilled and preloaded and use some of the thinnest needles available.a The pens can even be stored outside of the refrigerator for up to 21 days after first use.
Kissling Wurth –
I have taken this product for a couple of months. It really helps keep my appetite in check, positively impacts my energy levels and has helped in hardening my muscles. Highly recommend it!!
Walter Peter –
“I had my doubts at first but after taking this product for 30 days I have to say I’m amazed at the results! I’ve definitely seen a decrease in fat that was near impossible to get rid of and have become much more cut. I feel fine, i sleep even better, and just feel younger again.
Dorcas E –
Great product, awesome customer services.
This Online dispensary is good
Blandine B –
This stuff actually works. I feel stronger, have more energy and have started to lose weight. It takes about a couple of weeks to make a noticeable difference but you will notice it once you start to pay attention to what is going on. Great Products!
I will keep buying
Paul George –
einer der Bestseller von hgh
karl Max –
All my doubts were cleared after i recieved my products, its been 3 weeks since i started taking it and all looks well and positive so far.
Synotta B –
I was skeptical at first but after taking this product for 40 days I have to say I’m amazed at the results! I’ve definitely seen a decrease in fat that was near impossible to get rid of and have become much more cut.
Mason Green –
Product recieved in Australia in Good condition. Customer service too was lit. This online store is highly recommemnded
Benji –
A good product for growth development
Lilian Pam –
Product works great, been using it for a while now
Sheriff W –
Started out with .05 iu every day/two days off. then work up very slowly on dosage. I started off to high and resulted in edema/blood pressure issues. I lowered my dosage and inject twice daily with .07 iu per injection.I began to notice the positive effects after 90 days. expect to stay on HGH in order to reap the full benefits